Postdoctoral Researcher in AI-Based Multimodal Data Integration for Neurodegenerative Disease

Your role

You will work within a multidisciplinary environment together with experimental neuroscientists, bioinformaticians, mathematical modellers and software engineers. Your research will focus on developing ML- and AI-supported methods and tools to analyse heterogenous multimodal data generated from different neurodegenerative models including investigations on the impact of microgravity in collaboration with the company Exobiosphere.

Your responsibilities include:

• Developing and applying ML- and AI-based methods to multimodal datasets: multiomics, imaging, functional data
• Designing and implementing corresponding pipelines for automated data analyses
• Designing and implementing data structuring and harmonisation pipelines
• Analysing the effect of microgravity on brain cells
• Collaborating closely with experimentalists, data analysists and space scientist to develop integrative workflows
• Supporting documentation, reproducibility, and dissemination of research outputs: scientific publications, presentations, consortium deliverables

For further information, please contact Alexander Skupin: alexander.skupin@uni.lu

Your profile

Core qualifications:

• PhD in bioinformatics, computer science, computational biology, physics, data science, or related fields
• Strong interest in interdisciplinary and translational research
• Experience with programming skills in Julia, Python, C/C++ including machine learning and AI frameworks, e.g., PyTorch and TensorFlow
• Experience with omics data management, data preprocessing, and handling heterogeneous datasets
• Familiarity with SQL and basic database concepts

Desirable:

• Experience with deep learning, transformers, LLMs, generative AI and HPC clusters
• Experience with multiomics and multimodal data integration
• Background in neuroscience and neurodegeneration is an asset but not required
• Experience in interdisciplinary collaborations would be an add-on

Personal Skills:

• Open-minded, critical thinker with strong analytical and problem-solving skills
• Interdisciplinary mind-setting and good communication skills are essential
• Strong organisational, writing, and documentation skills

Language Requirements:

• The working language at the institute is English and a professional level (C1) is expected

We offer

• A modern, dynamic university with a personal and inclusive atmosphere. Multilingual and international character. Staff coming from more than 90 countries. Member of The Guild of European Research Intensive Universities
• An exceptional research environment, supported by skilled staff and high-quality equipment. Strong links to professional sectors and the Luxembourg labour market. A unique urban campus with excellent infrastructure
• A partner for society and industry. Cooperation with European institutions, innovative companies, the Financial Centre and a wide range of non-academic partners including ministries, local governments, associations, and NGOs

How to apply

Applications should include:

• Curriculum Vitae
• Cover letter detailing your motivation for applying to the advertised research topic and/or project, including how your background, interests, and career goals align with its objective
• PhD diploma or a letter/information indicating the expected defense date
• Transcript of all modules and results from university-level courses taken
• List of publications

Early application is highly encouraged, as the applications will be processed upon reception. Please apply ONLINE formally through the HR system. Applications by Email will not be considered.

All qualified individuals are encouraged to apply. In line with our values, the University of Luxembourg promotes an inclusive culture. We encourage applications from individuals of all backgrounds and are dedicated to upholding equality and respect for our employees and students.

General information:

• Contract Type: Fixed Term Contract 24 Month
• Work Hours: Full Time 40.0 Hours per Week
• Location: Belval Campus
• Internal Title: Postdoctoral researcher
• Job Reference: UOL08408

The yearly gross salary for every Postdoctoral Researcher at the UL is EUR 87306 (full time).

About us

The University of Luxembourg is an international research university with a distinctly multilingual and interdisciplinary character.

The Luxembourg Centre for Systems Biomedicine (LCSB) is an interdisciplinary research centre of the University of Luxembourg.We conduct fundamental and translational research in the field of Systems Biology and Biomedicine – in the lab, in the clinic and in silico. We focus on neurodegenerative processes and are especially interested in Alzheimer’s and Parkinson’s disease and their contributing factors. The LCSB recruits talented scientists from various disciplines: computer scientists, mathematicians, biologists, chemists, engineers, physicists and clinicians from more than 50 countries currently work at the LCSB. We excel because we are truly interdisciplinary, and together we contribute to science and society.

The successful candidate will join the Integrative Cell Signalling group led by Prof. Dr. Alexander Skupin, which focuses on multiscale biology of neurodegeneration by combining multiomics and imaging characterization of stem cell-derived brain cells with advanced bioinformatics approaches and mechanistic modelling. Our main interest is how perturbed brain energy metabolism contributes to brain disorders including Parkinson’s disease, Alzheimer’s disease, epilepsy and others. For more information, please visit our page.